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Anti-FREAC3 Polyclonal Antibody 2

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Catalog No. TMAB-06162

Anti-FREAC3 Polyclonal Antibody 2 is a Rabbit antibody targeting FREAC3. Anti-FREAC3 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF,FCM.

Anti-FREAC3 Polyclonal Antibody 2

Anti-FREAC3 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-06162
Anti-FREAC3 Polyclonal Antibody 2 is a Rabbit antibody targeting FREAC3. Anti-FREAC3 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FREAC3 Polyclonal Antibody 2 is a Rabbit antibody targeting FREAC3. Anti-FREAC3 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Cow,Horse)
Application
WB
IHC-P
IHC-Fr
IF
FCM
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityExpressed in all tissues and cell lines examined.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundBinding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Involvement in disease; Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3); also known as Axenfeld-Rieger syndrome (ARS) or Axenfeld syndrome or Axenfeld anomaly. It is characterized by posterior corneal embryotoxon, prominent Schwalbe line and iris adhesion to the Schwalbe line. Other features may be hypertelorism (wide spacing of the eyes), hypoplasia of the malar bones, congenital absence of some teeth and mental retardation. When associated with tooth anomalies, the disorder is known as Rieger syndrome. Glaucoma is a progressive blinding condition that occurs in approximately half of patients with Axenfeld-Rieger malformations.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FOXC1/FREAC3
Antigen Species
Human
Gene Name
FOXC1
Gene ID
2296
Protein Name
Forkhead box protein C1
Uniprot ID
Q12948
Function
Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees.
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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