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Anti-CD34 Polyclonal Antibody 2
Catalog No. TMAB-03958 Copy Product Info
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Anti-CD34 Polyclonal Antibody 2 is a Rabbit antibody targeting CD34. Anti-CD34 Polyclonal Antibody 2 can be used in WB.
Anti-CD34 Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-03958
Anti-CD34 Polyclonal Antibody 2 is a Rabbit antibody targeting CD34. Anti-CD34 Polyclonal Antibody 2 can be used in WB.
Anti-CD34 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD34 Polyclonal Antibody 2 is a Rabbit antibody targeting CD34. Anti-CD34 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with CD34 polyclonal antibody, unconjugated (TMAB-03958) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:1000-5000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence. |
| Immunogen | KLH conjugated synthetic peptide: human CD34 |
| Antigen Species | Human |
| Gene Name | CD34 |
| Gene ID | |
| Protein Name | Hematopoietic progenitor cell antigen CD34 |
| Uniprot ID | |
| Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
| Molecular Weight | Theoretical: 39 kDa. Actual: 80-120 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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