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Anti-Desmoglein 3 Polyclonal Antibody
Catalog No. TMAB-05102 Copy Product Info
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Anti-Desmoglein 3 Polyclonal Antibody is a Rabbit antibody targeting Desmoglein 3. Anti-Desmoglein 3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Desmoglein 3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-05102
Anti-Desmoglein 3 Polyclonal Antibody is a Rabbit antibody targeting Desmoglein 3. Anti-Desmoglein 3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Desmoglein 3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Desmoglein 3 Polyclonal Antibody is a Rabbit antibody targeting Desmoglein 3. Anti-Desmoglein 3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Rabbit) |
| Verified Activity | Tissue/cell: rat tongue tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-Desmoglein 3 Polyclonal Antibody, Unconjugated (TMAB-05102) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. |
| Tissue Specificity | Epidermis, tongue, tonsil, esophagus and carcinomas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. |
| Immunogen | KLH conjugated synthetic peptide: human Desmoglein 3 |
| Antigen Species | Human |
| Gene Name | DSG3 |
| Gene ID | |
| Protein Name | Desmoglein-3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 105 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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