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Anti-TCF12 Polyclonal Antibody

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Catalog No. TMAB-13422

Anti-TCF12 Polyclonal Antibody is a Rabbit antibody targeting TCF12. Anti-TCF12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-TCF12 Polyclonal Antibody

Anti-TCF12 Polyclonal Antibody

😃Good
Catalog No. TMAB-13422
Anti-TCF12 Polyclonal Antibody is a Rabbit antibody targeting TCF12. Anti-TCF12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TCF12 Polyclonal Antibody is a Rabbit antibody targeting TCF12. Anti-TCF12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Horse,Rabbit,Zebrafish,Sheep)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityExpressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDifferentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TCF12
Antigen Species
Human
Gene Name
TCF12
Gene ID
6938
Protein Name
Transcription factor 12
Uniprot ID
Q99081
Function
Binds specifically to oligomers of E-box motifs. May play important roles during development of the nervous system as well as in other organ systems.
Chemical Properties
Molecular WeightTheoretical: 73 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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