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Anti-TCF12 Polyclonal Antibody
Catalog No. TMAB-13422 Copy Product Info
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Anti-TCF12 Polyclonal Antibody is a Rabbit antibody targeting TCF12. Anti-TCF12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-TCF12 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13422
Anti-TCF12 Polyclonal Antibody is a Rabbit antibody targeting TCF12. Anti-TCF12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-TCF12 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Bioactivity
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| Description | Anti-TCF12 Polyclonal Antibody is a Rabbit antibody targeting TCF12. Anti-TCF12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Horse,Rabbit,Zebrafish,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Rat colon); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (TCF12) Polyclonal Antibody, Unconjugated (TMAB-13422) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression. |
| Immunogen | KLH conjugated synthetic peptide: human TCF12 |
| Antigen Species | Human |
| Gene Name | TCF12 |
| Gene ID | |
| Protein Name | Transcription factor 12 |
| Uniprot ID | |
| Function | Binds specifically to oligomers of E-box motifs. May play important roles during development of the nervous system as well as in other organ systems. |
| Molecular Weight | Theoretical: 73 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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