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Anti-GTPBP3 Polyclonal Antibody
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Catalog No. TMAB-06852 Copy Product Info
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Anti-GTPBP3 Polyclonal Antibody is a Rabbit antibody targeting GTPBP3. Anti-GTPBP3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-GTPBP3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $220 | 7-10 days | 7-10 days | |
| 100 µL | $374 | 7-10 days | 7-10 days | |
| 200 µL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GTPBP3 Polyclonal Antibody is a Rabbit antibody targeting GTPBP3. Anti-GTPBP3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Horse) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MSS1) Polyclonal Antibody, Unconjugated (TMAB-06852) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (mouse spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MSS1) Polyclonal Antibody, Unconjugated (TMAB-06852) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrial |
| Tissue Specificity | Ubiquitously expressed. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2010] |
| Immunogen | KLH conjugated synthetic peptide: human MSS1 |
| Antigen Species | Human |
| Gene Name | GTPBP3 |
| Gene ID | |
| Protein Name | tRNA modification GTPase GTPBP3, mitochondrial |
| Uniprot ID | |
| Function | The GTPBP3 is the mitochondrial GTPase evolutionarily conserved from bacteria to mammals. GTPBP3 is ubiquitously expressed in various tissues. GTPBP3 localizes in mitochondrion. The human GTPBP3 is a deafness associated homolog of yeast MSS1. The allelic variants in GTPBP3 could modulate the phenotypic manifestation of human mitochondrial A1555G mutation. GTPBP3 may be involved in the 5 carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. |
| Molecular Weight | Theoretical: 48 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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