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Anti-ABCD4 Polyclonal Antibody is a Rabbit antibody targeting ABCD4. Anti-ABCD4 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-ABCD4 Polyclonal Antibody is a Rabbit antibody targeting ABCD4. Anti-ABCD4 Polyclonal Antibody can be used in WB. |
| Synonyms | XMP 1L, PXMP1-L, PXMP1L, PXMP1 L, PMP70-related protein, PMP69, PMP 69, Peroxisomal membrane protein 69, Peroxisomal membrane protein 1-like, Peroxisomal membrane protein 1 like, P70R antibodyP79R, ATP-binding cassette sub-family D member 4, ATP binding cassette sub family D(ALD) member 4, ATP binding cassette sub family D member 4, ABCD4_HUMAN, ABCD4, ABCD 4, ABC41, ABC 41 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Sample: A431 Cell (Human) Lysate at 30 μg Primary: Anti-ABCD4 (TMAB-02155) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 69 kD Observed band size: 69 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Peroxisome membrane; Multi-pass membrane protein. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 gene causes X-linked adreno-leukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises two quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD1 localizes to peroxisomes. ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol. |
| Immunogen | KLH conjugated synthetic peptide: human ABCD4 |
| Antigen Species | Human |
| Gene Name | ABCD4 |
| Gene ID | |
| Protein Name | Lysosomal cobalamin transporter ABCD4 |
| Uniprot ID |
| Molecular Weight | Theoretical: 69 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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