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Anti-APLP1 Polyclonal Antibody

Catalog No. TMAB-02750 Copy Product Info
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Anti-APLP1 Polyclonal Antibody is a Rabbit antibody targeting APLP1. Anti-APLP1 Polyclonal Antibody can be used in WB.

Anti-APLP1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-02750

Anti-APLP1 Polyclonal Antibody is a Rabbit antibody targeting APLP1. Anti-APLP1 Polyclonal Antibody can be used in WB.

Anti-APLP1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-APLP1 Polyclonal Antibody is a Rabbit antibody targeting APLP1. Anti-APLP1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Sheep)
Verified Activity
Sample:
Brain (Mouse) Lysate at 40 μg
Primary: Anti-APLP1 (TMAB-02750) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 68 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane and Cytoplasm. C-terminally processed in the Golgi complex.
Tissue SpecificityExpressed in the cerebral cortex where it is localized to the postsynaptic density (PSD).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMay play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human APLP1
Antigen Species
Human
Gene Name
APLP1
Gene ID
Protein Name
Amyloid-like protein 1
Uniprot ID
Function
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis (By similarity).
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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