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Anti-CLSTN2 Polyclonal Antibody

Catalog No. TMAB-04470 Copy Product Info
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Anti-CLSTN2 Polyclonal Antibody is a Rabbit antibody targeting CLSTN2. Anti-CLSTN2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CLSTN2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04470

Anti-CLSTN2 Polyclonal Antibody is a Rabbit antibody targeting CLSTN2. Anti-CLSTN2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CLSTN2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CLSTN2 Polyclonal Antibody is a Rabbit antibody targeting CLSTN2. Anti-CLSTN2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Pig,Cow,Horse,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse cerebellum); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CLSTN2) Polyclonal Antibody, Unconjugated (TMAB-04470) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein (Potential). Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization (By similarity).
Tissue SpecificityRestricted to the brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMembers of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-2, also known as Alcadein-gamma, is a 955 amino acid protein that localizes to the endoplasmic reticulum, golgi apparatus and plasma membranes. Containing 2 cadherin-like repeats in its N-terminal extracellular region, calsyntenin-2 binds synaptic calcium with its cytoplasmic domain, suggesting a role in the modulation of calcium-mediated postsynaptic signals. Under normal physiological conditions, calsyntenin-2 is protoeolytically processed in an event in which the primary zeta-cleavage generates a short C-terminal transmembrane fragment and a long extracellular N-terminal domain.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CLSTN2
Antigen Species
Human
Gene Name
CLSTN2
Gene ID
Protein Name
Calsyntenin-2
Uniprot ID
Function
May modulate calcium-mediated postsynaptic signals.
Chemical Properties
Molecular WeightTheoretical: 105 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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