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Anti-SHC4 Polyclonal Antibody
😃Good
Catalog No. TMAB-12766
Anti-SHC4 Polyclonal Antibody is a Rabbit antibody targeting SHC4. Anti-SHC4 Polyclonal Antibody can be used in WB.
Anti-SHC4 Polyclonal Antibody
Anti-SHC4 Polyclonal Antibody
😃Good
Catalog No. TMAB-12766
Anti-SHC4 Polyclonal Antibody is a Rabbit antibody targeting SHC4. Anti-SHC4 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SHC4 Polyclonal Antibody is a Rabbit antibody targeting SHC4. Anti-SHC4 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction > synapse > postsynaptic cell membrane. Colocalized with MUSK at the neuromuscular junction. |
| Tissue Specificity | Only expressed in melanomas. Weakly expressed in normal melanocytes and benign nevi. Highly expressed at the transition from radial growth phase to vertical growth phase and metastatic melanomas, when tumor cells acquire migratory competence and invasive potential. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Immunogen | KLH conjugated synthetic peptide: human SHC4 |
| Antigen Species | Human |
| Gene Name | SHC4 |
| Gene ID | |
| Protein Name | SHC-transforming protein 4 |
| Uniprot ID | |
| Function | Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1. |
| Molecular Weight | Theoretical: 69 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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