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Anti-RRAGD Polyclonal Antibody

Catalog No. TMAB-12388 Copy Product Info
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Anti-RRAGD Polyclonal Antibody is a Rabbit antibody targeting RRAGD. Anti-RRAGD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-RRAGD Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-12388

Anti-RRAGD Polyclonal Antibody is a Rabbit antibody targeting RRAGD. Anti-RRAGD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-RRAGD Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-RRAGD Polyclonal Antibody is a Rabbit antibody targeting RRAGD. Anti-RRAGD Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (RRAGD) Polyclonal Antibody, Unconjugated (TMAB-12388) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Lysosome. Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundRRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human RRAGD
Antigen Species
Human
Gene Name
RRAGD
Gene ID
Protein Name
Ras-related GTP-binding protein D
Uniprot ID
Function
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.
Chemical Properties
Molecular WeightTheoretical: 45 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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