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Anti-CK14+17+42+10 Polyclonal Antibody

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Catalog No. TMAB-04387

Anti-CK14+17+42+10 Polyclonal Antibody is a Rabbit antibody targeting CK14+17+42+10. Anti-CK14+17+42+10 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-CK14+17+42+10 Polyclonal Antibody

Anti-CK14+17+42+10 Polyclonal Antibody

😃Good
Catalog No. TMAB-04387
Anti-CK14+17+42+10 Polyclonal Antibody is a Rabbit antibody targeting CK14+17+42+10. Anti-CK14+17+42+10 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CK14+17+42+10 Polyclonal Antibody is a Rabbit antibody targeting CK14+17+42+10. Anti-CK14+17+42+10 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern.
Tissue SpecificityDetected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CK14
Antigen Species
Human
Gene Name
KRT14
Gene ID
Protein Name
Keratin, type I cytoskeletal 14
Uniprot ID
Function
The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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