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Anti-RYBP Polyclonal Antibody
😃Good
Catalog No. TMAB-12438
Anti-RYBP Polyclonal Antibody is a Rabbit antibody targeting RYBP. Anti-RYBP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-RYBP Polyclonal Antibody
Anti-RYBP Polyclonal Antibody
😃Good
Catalog No. TMAB-12438
Anti-RYBP Polyclonal Antibody is a Rabbit antibody targeting RYBP. Anti-RYBP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-RYBP Polyclonal Antibody is a Rabbit antibody targeting RYBP. Anti-RYBP Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Cow,Horse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Nucleus, nucleoplasm. Note=Primarily found in the nucleus. Detected in a punctate pattern likely to represent Polycomb group (PcG) bodies |
| Tissue Specificity | Widely expressed with highest levels in lymphoid tissues and placenta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. In tumor cell lines, may induce apoptosis. |
| Immunogen | KLH conjugated synthetic peptide: human AAP1 |
| Antigen Species | Human |
| Gene Name | RYBP |
| Gene ID | |
| Protein Name | RING1 and YY1-binding protein |
| Uniprot ID | |
| Function | nhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis. |
| Molecular Weight | Theoretical: 24 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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