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Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2

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Catalog No. TMAB-11319

Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-SREBP2 (Thr334). Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2 can be used in WB.

Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2

Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2

😃Good
Catalog No. TMAB-11319
Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-SREBP2 (Thr334). Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-SREBP2 (Thr334). Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Pig,Cow,Horse)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. Processed sterol regulatory element-binding protein 2: Nucleus.
Tissue SpecificityUbiquitously expressed in adult and fetal tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants.
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human SREBP2 around the phosphorylation site of Thr334
Antigen Species
Human
Gene Name
SREBF2
Gene ID
6721
Protein Name
Sterol regulatory element-binding protein 2
Uniprot ID
Q12772
Function
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Chemical Properties
Molecular WeightTheoretical: 126 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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