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Anti-beta Adducin Polyclonal Antibody

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Catalog No. TMAB-03095

Anti-beta Adducin Polyclonal Antibody is a Rabbit antibody targeting beta Adducin. Anti-beta Adducin Polyclonal Antibody can be used in WB.

Anti-beta Adducin Polyclonal Antibody

Anti-beta Adducin Polyclonal Antibody

😃Good
Catalog No. TMAB-03095
Anti-beta Adducin Polyclonal Antibody is a Rabbit antibody targeting beta Adducin. Anti-beta Adducin Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-beta Adducin Polyclonal Antibody is a Rabbit antibody targeting beta Adducin. Anti-beta Adducin Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Rat
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane-cytoskeleton-associated protein.
Tissue SpecificityExpressed mainly in brain, spleen, kidney cortex and medulla, and heart. Also expressed in human umbilical vein endothelial cells, human vascular smooth muscle cells, kidney tubular cells and K-562 cell line.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundAdducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human beta Adducin protein
Antigen Species
Human
Gene Name
ADD2
Gene ID
119
Protein Name
beta-adducin
Uniprot ID
P35612
Function
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
Chemical Properties
Molecular WeightTheoretical: 80 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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