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Anti-Netrin G1 ligand Polyclonal Antibody

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Catalog No. TMAB-09368

Anti-Netrin G1 ligand Polyclonal Antibody is a Rabbit antibody targeting Netrin G1 ligand. Anti-Netrin G1 ligand Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Netrin G1 ligand Polyclonal Antibody

Anti-Netrin G1 ligand Polyclonal Antibody

😃Good
Catalog No. TMAB-09368
Anti-Netrin G1 ligand Polyclonal Antibody is a Rabbit antibody targeting Netrin G1 ligand. Anti-Netrin G1 ligand Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Netrin G1 ligand Polyclonal Antibody is a Rabbit antibody targeting Netrin G1 ligand. Anti-Netrin G1 ligand Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Cow,Horse,Rabbit)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
Tissue SpecificityHighly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show very weak or no expression.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNGL-1 is a single pass type I membrane protein that acts as a cell adhesion molecule. It contains nine leucine-rich repeats (LRR) and one Ig-like C2-type domain. NGL-1 is predominantly expressed in the striatum and the cerebral cortex of both the embryonic and adult brain. NGL-1 specifically interacts with Netrin G1 (a molecule involved in axon guidance in the developing central nervous system) via its LRR region. NGL-1 plays a role in the regulation of neurite outgrowth of developing thalamic neurons. Soluble NGL-1 inhibits thalamic axon outgrowth while NGL-1 that is bound to the surface of developing thalamocortical axons stimulates growth. NGL-1 also interacts with Whirlin possibly stablizing interstereociliar links.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Netrin G1 ligand
Antigen Species
Human
Gene Name
LRRC4C
Gene ID
57689
Protein Name
Leucine-rich repeat-containing protein 4C
Uniprot ID
Q9HCJ2
Function
May promote neurite outgrowth of developing thalamic neurons.
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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