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Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody

Catalog No. TMAB-10352 Copy Product Info
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Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATF4 (Ser245). Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody can be used in WB.

Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-10352

Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATF4 (Ser245). Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody can be used in WB.

Anti-Phospho-ATF4
(Ser245) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATF4 (Ser245). Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample: A431 (Human) Cell Lysate at 30 μg
Primary: Anti-phospho-ATF4 (Ser245) (TMAB-10352) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 38 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cell membrane. Nucleus. Colocalizes with GABBR1 in hippocampal neuron dendritic membranes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human ATF4 around the phosphorylation site of Ser245
Antigen Species
Human
Gene Name
ATF4
Gene ID
468
Protein Name
Cyclic AMP-dependent transcription factor ATF-4
Uniprot ID
P18848
Function
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
Chemical Properties
Molecular WeightTheoretical: 38 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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