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Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody
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Catalog No. TMAB-10352
Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATF4 (Ser245). Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody can be used in WB.
Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody
Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody
😃Good
Catalog No. TMAB-10352
Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATF4 (Ser245). Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATF4 (Ser245). Anti-Phospho-ATF4 (Ser245) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell membrane. Nucleus. Colocalizes with GABBR1 in hippocampal neuron dendritic membranes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene). |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human ATF4 around the phosphorylation site of Ser245 |
| Antigen Species | Human |
| Gene Name | ATF4 |
| Gene ID | |
| Protein Name | Cyclic AMP-dependent transcription factor ATF-4 |
| Uniprot ID | |
| Function | Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. |
| Molecular Weight | Theoretical: 38 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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