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Anti-5HT1B Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT1B Receptor. Anti-5HT1B Receptor Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-5HT1B Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT1B Receptor. Anti-5HT1B Receptor Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Synonyms | Serotonin receptor 1B, Serotonin 1D beta receptor, S12, HTR1DB, HTR1D2, HTR1B, HTR 1B, 5-hydroxytryptamine receptor 1B, 5-HT-1D-beta, 5-HT1BR, 5HT1BR, 5HT1B_HUMAN, 5HT1B Receptor, 5-HT-1B, 5-HT1B, 5 hydroxytryptamine(serotonin) receptor 1B, 5 hydroxytryptamine receptor 1B, 5 HT1DB, 5 HT1B receptor, 5 HT1B, 5 HT 1D beta, 5 HT 1B |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | 1. Tissue/cell: rat brain tissue (Snr); 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-5-HTR1B Polyclonal Antibody, Unconjugated (TMAB-02098) 1:300, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining 2. Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Placenta tissue lysates Lane 3: Rat Cerebrum tissue lysates Primary: Anti-5HT1B Receptor (TMAB-02098) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kDa Observed band size: 48 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM, Oct 2009]. |
| Immunogen | KLH conjugated synthetic peptide: human 5-HTR1B |
| Antigen Species | Human |
| Gene Name | HTR1B |
| Gene ID | |
| Protein Name | 5-hydroxytryptamine receptor 1B |
| Uniprot ID | |
| Function | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
| Molecular Weight | Theoretical: 44 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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