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Anti-MCT2 Polyclonal Antibody

Catalog No. TMAB-08681 Copy Product Info
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Anti-MCT2 Polyclonal Antibody is a Rabbit antibody targeting MCT2. Anti-MCT2 Polyclonal Antibody can be used in WB.

Anti-MCT2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08681

Anti-MCT2 Polyclonal Antibody is a Rabbit antibody targeting MCT2. Anti-MCT2 Polyclonal Antibody can be used in WB.

Anti-MCT2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-MCT2 Polyclonal Antibody is a Rabbit antibody targeting MCT2. Anti-MCT2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat
Verified Activity
Sample:
Cerebrum (Mouse) Lysate at 40 μg
Cerebrum (Rat) Lysate at 40 μg
Cerebellum (Mouse) Lysate at 40 μg
Cerebellum (Rat) Lysate at 40 μg
Spinal cord (Mouse) Lysate at 40 μg
Spinal cord (Rat) Lysate at 40 μg
Primary: Anti-MCT2 (TMAB-08681) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 50 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityHigh expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundTissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]).[supplied by OMIM, Feb 2011].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse MCT2
Antigen Species
Mouse
Gene Name
SLC16A7
Gene ID
Protein Name
Monocarboxylate transporter 2
Function
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter.
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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