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Anti-C11ORF77 Polyclonal Antibody

Catalog No. TMAB-03294 Copy Product Info
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Anti-C11ORF77 Polyclonal Antibody is a Rabbit antibody targeting C11ORF77. Anti-C11ORF77 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-C11ORF77 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-03294

Anti-C11ORF77 Polyclonal Antibody is a Rabbit antibody targeting C11ORF77. Anti-C11ORF77 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-C11ORF77 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-C11ORF77 Polyclonal Antibody is a Rabbit antibody targeting C11ORF77. Anti-C11ORF77 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (C11ORF77) Polyclonal Antibody, Unconjugated (TMAB-03294) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Interaction with NAIF1 promotes translocation to the nucleus.
Tissue SpecificityDetected in brain, eye, nerve tissue, kidney and lung.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHARBI1 is a 349 amino acid nuclear and cytoplasmic protein belonging to the HARBI1 family. Members of the HARBI1 family of proteins are highly conserved in humans to various bony fish. Considered a transposase-derived protein, HARBI1 may possess nuclease activity and is expressed in brain, eye, nerve tissue, kidney and lung. HARBI1 utilizes divalent metal cations as cofactors, interacts with NAIF1 and promotes translocation to the nucleus. HARBI1 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human C11ORF77/HARBI1
Antigen Species
Human
Gene Name
HARBI1
Gene ID
Protein Name
Putative nuclease HARBI1
Uniprot ID
Function
Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.
Chemical Properties
Molecular WeightTheoretical: 39 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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