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Anti-ZDHHC2/ZNF372 Polyclonal Antibody is a Rabbit antibody targeting ZDHHC2/ZNF372. Anti-ZDHHC2/ZNF372 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-ZDHHC2/ZNF372 Polyclonal Antibody is a Rabbit antibody targeting ZDHHC2/ZNF372. Anti-ZDHHC2/ZNF372 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Horse,Rabbit,Monkey) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Ubiquitously expressed. Reduced expression in colorectal cancers with liver metastasis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ZDHHC2 is a 367 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. The ubiquitously expressed ZDHHC2 protein functions as a palmitoyltransferase that uses palmitoyl-CoA and catalyzes the conversion of target proteins, namely GAP-43 and PSD-95, to S-palmitoyl proteins. Defects in the gene encoding ZDHHC2 are found in colorectal cancer and hepatocellular carcinoma, suggesting a role for ZDHHC2 in tumorigenesis. The gene encoding human ZDHHC2 maps to chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. |
| Immunogen | KLH conjugated synthetic peptide: human ZDHHC2/ZNF372 |
| Antigen Species | Human |
| Gene Name | ZDHHC2 |
| Gene ID | |
| Protein Name | Palmitoyltransferase ZDHHC2 |
| Uniprot ID | |
| Function | Palmitoyltransferase specific for GAP43 and DLG4/PSD95. |
| Molecular Weight | Theoretical: 42 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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