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Anti-GPD1L Polyclonal Antibody

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Catalog No. TMAB-06665

Anti-GPD1L Polyclonal Antibody is a Rabbit antibody targeting GPD1L. Anti-GPD1L Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-GPD1L Polyclonal Antibody

Anti-GPD1L Polyclonal Antibody

😃Good
Catalog No. TMAB-06665
Anti-GPD1L Polyclonal Antibody is a Rabbit antibody targeting GPD1L. Anti-GPD1L Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GPD1L Polyclonal Antibody is a Rabbit antibody targeting GPD1L. Anti-GPD1L Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Sheep)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Localized to the region of the plasma membrane.
Tissue SpecificityMost highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GPD1L
Antigen Species
Human
Gene Name
GPD1L
Gene ID
Protein Name
Glycerol-3-phosphate dehydrogenase 1-like protein
Uniprot ID
Function
Play a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
Chemical Properties
Molecular WeightTheoretical: 38 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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