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Anti-ZDHHC3 Polyclonal Antibody
😃Good
Catalog No. TMAB-14282
Anti-ZDHHC3 Polyclonal Antibody is a Rabbit antibody targeting ZDHHC3. Anti-ZDHHC3 Polyclonal Antibody can be used in WB.
Anti-ZDHHC3 Polyclonal Antibody
Anti-ZDHHC3 Polyclonal Antibody
😃Good
Catalog No. TMAB-14282
Anti-ZDHHC3 Polyclonal Antibody is a Rabbit antibody targeting ZDHHC3. Anti-ZDHHC3 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ZDHHC3 Polyclonal Antibody is a Rabbit antibody targeting ZDHHC3. Anti-ZDHHC3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Golgi apparatus membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Golgi-specific DHHC (Asp-His-His-Cys) zinc finger protein (GODZ), also known as, Palmitoyltransferase ZDHHC3 or Zinc finger protein 373, is a 327 amino acid protein member of the DHHC palmitoyltransferase family. Localized to the Golgi apparatus membrane, GODZ contains one DHHC-type zinc finger, which is necessary for its palmitoyltransferase activity. GODZ has been implicated in the palmitoylation and regulated trafficking of diverse substrates that function various inhibitory and excitatory synapses. Specifically, it palmitoylates the gamma subunit 2 of GABA(A) receptors, which leads to normal synaptic GABAergic inhibitory function. GODZ also palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. Two isoforms of GODZ exist as a result of alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human GODZ/ZNF373 |
| Antigen Species | Human |
| Gene Name | ZDHHC3 |
| Gene ID | |
| Protein Name | Palmitoyltransferase ZDHHC3 |
| Uniprot ID | |
| Function | Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. |
| Molecular Weight | Theoretical: 34 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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