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Anti-C1orf80 Polyclonal Antibody
Catalog No. TMAB-03361 Copy Product Info
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Anti-C1orf80 Polyclonal Antibody is a Rabbit antibody targeting C1orf80. Anti-C1orf80 Polyclonal Antibody can be used in WB.
Anti-C1orf80 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-03361
Anti-C1orf80 Polyclonal Antibody is a Rabbit antibody targeting C1orf80. Anti-C1orf80 Polyclonal Antibody can be used in WB.
Anti-C1orf80 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-C1orf80 Polyclonal Antibody is a Rabbit antibody targeting C1orf80. Anti-C1orf80 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse) |
| Verified Activity | Sample: K562 Cell (Human) Lysate at 40 μg Primary: Anti-C1orf80 (TMAB-03361) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 35 kD Observed band size: 34 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Widely expressed in adult tissues, with highest expression in the heart and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | AIDA, also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human C1orf180/AIDA |
| Antigen Species | Human |
| Gene Name | AIDA |
| Gene ID | |
| Protein Name | Axin interactor, dorsalization-associated protein |
| Uniprot ID | |
| Function | Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity). |
| Molecular Weight | Theoretical: 35 kDa. Actual: 34 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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