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Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody
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Catalog No. TMAB-10534
Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Thr466). Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody can be used in WB.
Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody
Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody
😃Good
Catalog No. TMAB-10534
Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Thr466). Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Thr466). Anti-Phospho-Cortactin (Thr466) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010] |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human Cortactin around the phosphorylation site of Thr466 |
| Antigen Species | Human |
| Gene Name | CTTN |
| Gene ID | |
| Protein Name | Src substrate cortactin |
| Uniprot ID | |
| Function | Contributes to the organization of the actin cytoskeleton and cell structure. Plays a role in the regulation of cell migration. Plays a role in the invasiveness of cancer cells, and the formation of metastases. |
| Molecular Weight | Theoretical: 61 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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