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Anti-MT-ND1 Polyclonal Antibody
😃Good
Catalog No. TMAB-09074
Anti-MT-ND1 Polyclonal Antibody is a Rabbit antibody targeting MT-ND1. Anti-MT-ND1 Polyclonal Antibody can be used in WB.
Anti-MT-ND1 Polyclonal Antibody
Anti-MT-ND1 Polyclonal Antibody
😃Good
Catalog No. TMAB-09074
Anti-MT-ND1 Polyclonal Antibody is a Rabbit antibody targeting MT-ND1. Anti-MT-ND1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MT-ND1 Polyclonal Antibody is a Rabbit antibody targeting MT-ND1. Anti-MT-ND1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion inner membrane; Multi-pass membrane protein |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | MT-ND1 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]; also known as Leber optic atrophy. LHON is a maternally inherited disease resulting in acute bilateral blindness due to retinal degeneration predominantly in young men. Cardiac conduction defects and neurological defects have also been described, resulting in optic nerve degeneration and cardiac dysrhythmia. Defects in MT-ND1 may also be associated with mitochondrial susceptibility to Alzheimer disease (AD) and non insulin dependent diabetes mellitus (NIDDM). |
| Immunogen | KLH conjugated synthetic peptide: human MT-ND1 |
| Antigen Species | Human |
| Gene Name | MT-ND1 |
| Gene ID | |
| Protein Name | NADH-ubiquinone oxidoreductase chain 1 |
| Uniprot ID | |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
| Molecular Weight | Theoretical: 36 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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