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Anti-GPR58 Polyclonal Antibody

Catalog No. TMAB-06726 Copy Product Info
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Anti-GPR58 Polyclonal Antibody is a Rabbit antibody targeting GPR58. Anti-GPR58 Polyclonal Antibody can be used in WB.

Anti-GPR58 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-06726

Anti-GPR58 Polyclonal Antibody is a Rabbit antibody targeting GPR58. Anti-GPR58 Polyclonal Antibody can be used in WB.

Anti-GPR58 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GPR58 Polyclonal Antibody is a Rabbit antibody targeting GPR58. Anti-GPR58 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Pig,Cow,Rabbit,Sheep)
Verified Activity
1. Sample: Cerebellum (Mouse) Lysate at 40 μg
Primary: Anti-GPR58 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kD
Observed band size: 50 kD
2. Sample:
placenta (Mouse) Lysate at 40 μg
Cerebrum (Mouse) Lysate at 40 μg
Primary: Anti-GPR58 (TMAB-06726) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kD
Observed band size: 50 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationIntegral membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundTrace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TAAR’s contain several structural features that are similar to the rhodopsin beta-adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder. TAAR-1 is a 340 amino acid protein that increases intracellular cAMP accumulation in response to beta-phenylethylamine and tyramine. TAAR-1 is associated with the detection of social cues, illustrating its significance as a therapeutic target.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GPR58
Antigen Species
Human
Gene Name
TAAR2
Gene ID
Protein Name
Trace amine-associated receptor 2
Uniprot ID
Function
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR58 is a member of this family (subfamily Orphan-A). GPR58 expression has not been reported from human liver and several brain areas.
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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