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Anti-KIR5.1 Polyclonal Antibody

😃Good
Catalog No. TMAB-08077

Anti-KIR5.1 Polyclonal Antibody is a Rabbit antibody targeting KIR5.1. Anti-KIR5.1 Polyclonal Antibody can be used in ELISA,WB.

Anti-KIR5.1 Polyclonal Antibody

Anti-KIR5.1 Polyclonal Antibody

😃Good
Catalog No. TMAB-08077
Anti-KIR5.1 Polyclonal Antibody is a Rabbit antibody targeting KIR5.1. Anti-KIR5.1 Polyclonal Antibody can be used in ELISA,WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KIR5.1 Polyclonal Antibody is a Rabbit antibody targeting KIR5.1. Anti-KIR5.1 Polyclonal Antibody can be used in ELISA,WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Horse,Rabbit)
Application
Recommended Dose
ELISA: 1:5000-10000; WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi pass membrane protein.
Tissue SpecificityHighly expressed in kidney, pancreas and thyroid gland.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human KIR5.1
Antigen Species
Human
Gene Name
KCNJ16
Gene ID
Protein Name
Inward rectifier potassium channel 16
Uniprot ID
Function
KIR5.1 is one of 20 members of the inwardly rectifying potassium (Kir) channel family. Due to its expression in kidney, pancreas and thyroid gland, it has been suggested that human KIR5.1 may be involved in the regulation of fluid and pH balance, thus making it a potential therapeutic target for hypertension, renal failure, or pancreatic disease.
Chemical Properties
Molecular WeightTheoretical: 48 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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