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Anti-SCN8A/Nav1.6 Polyclonal Antibody
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Catalog No. TMAB-12587
Anti-SCN8A/Nav1.6 Polyclonal Antibody is a Rabbit antibody targeting SCN8A/Nav1.6. Anti-SCN8A/Nav1.6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-SCN8A/Nav1.6 Polyclonal Antibody
Anti-SCN8A/Nav1.6 Polyclonal Antibody
😃Good
Catalog No. TMAB-12587
Anti-SCN8A/Nav1.6 Polyclonal Antibody is a Rabbit antibody targeting SCN8A/Nav1.6. Anti-SCN8A/Nav1.6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SCN8A/Nav1.6 Polyclonal Antibody is a Rabbit antibody targeting SCN8A/Nav1.6. Anti-SCN8A/Nav1.6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cytoplasm, perinuclear region. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation. |
| Immunogen | KLH conjugated synthetic peptide: human SCN8A/Nav1.6 |
| Antigen Species | Human |
| Gene Name | SCN8A |
| Gene ID | |
| Protein Name | Sodium channel protein type 8 subunit alpha |
| Uniprot ID | |
| Function | Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. |
| Molecular Weight | Theoretical: 220 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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