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Anti-GlyR alpha 1+2+3 Polyclonal Antibody

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Catalog No. TMAB-06587

Anti-GlyR alpha 1+2+3 Polyclonal Antibody is a Rabbit antibody targeting GlyR alpha 1+2+3. Anti-GlyR alpha 1+2+3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-GlyR alpha 1+2+3 Polyclonal Antibody

Anti-GlyR alpha 1+2+3 Polyclonal Antibody

😃Good
Catalog No. TMAB-06587
Anti-GlyR alpha 1+2+3 Polyclonal Antibody is a Rabbit antibody targeting GlyR alpha 1+2+3. Anti-GlyR alpha 1+2+3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GlyR alpha 1+2+3 Polyclonal Antibody is a Rabbit antibody targeting GlyR alpha 1+2+3. Anti-GlyR alpha 1+2+3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGlycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GlyR alpha 1
Antigen Species
Human
Gene Name
GLRA1
Gene ID
2741
Protein Name
Glycine receptor subunit alpha-1
Uniprot ID
P23415
Function
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Chemical Properties
Molecular WeightTheoretical: 49 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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