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Anti-OSMR Polyclonal Antibody 2
😃Good
Catalog No. TMAB-09814
Anti-OSMR Polyclonal Antibody 2 is a Rabbit antibody targeting OSMR. Anti-OSMR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Anti-OSMR Polyclonal Antibody 2
Anti-OSMR Polyclonal Antibody 2
😃Good
Catalog No. TMAB-09814
Anti-OSMR Polyclonal Antibody 2 is a Rabbit antibody targeting OSMR. Anti-OSMR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-OSMR Polyclonal Antibody 2 is a Rabbit antibody targeting OSMR. Anti-OSMR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF. |
| Immunogen | KLH conjugated synthetic peptide: human OSMR |
| Antigen Species | Human |
| Gene Name | OSMR |
| Gene ID | |
| Protein Name | Oncostatin-M-specific receptor subunit beta |
| Uniprot ID | |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Molecular Weight | Theoretical: 111 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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