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Anti-SORCS2 Polyclonal Antibody

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Catalog No. TMAB-13046

Anti-SORCS2 Polyclonal Antibody is a Rabbit antibody targeting SORCS2. Anti-SORCS2 Polyclonal Antibody can be used in WB.

Anti-SORCS2 Polyclonal Antibody

Anti-SORCS2 Polyclonal Antibody

😃Good
Catalog No. TMAB-13046
Anti-SORCS2 Polyclonal Antibody is a Rabbit antibody targeting SORCS2. Anti-SORCS2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SORCS2 Polyclonal Antibody is a Rabbit antibody targeting SORCS2. Anti-SORCS2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single pass type I membrane protein.
Tissue SpecificityHighly expressed in brain and kidney. Detected at low levels in heart, liver, small intestine, skeletal muscle and thymus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThere are three SorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, SorCS1, SorCS2 and SorCS3 genes are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS2 (sortilin-related VPS10 domain containing receptor 2) is a 1,150 amino acid single-pass type I membrane protein that is highly expressed in brain and kidney. Containing six BNR repeats and a single PKD domain, SorCS2 is encoded by a gene that maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SORCS2
Antigen Species
Human
Gene Name
SORCS2
Gene ID
Protein Name
VPS10 domain-containing receptor SorCS2
Uniprot ID
Function
SORCS2 is a member of the vacuolar protein sorting 10 (VPS10) domain containing receptor protein family. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. These proteins are strongly expressed in the central nervous system.
Chemical Properties
Molecular WeightTheoretical: 123 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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