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Anti-AKR1B10 Polyclonal Antibody
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Catalog No. TMAB-02406 Copy Product Info
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Anti-AKR1B10 Polyclonal Antibody is a Rabbit antibody targeting AKR1B10. Anti-AKR1B10 Polyclonal Antibody can be used in WB.
Anti-AKR1B10 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $223 | 7-10 days | 7-10 days | |
| 100 µL | $372 | 7-10 days | 7-10 days | |
| 200 µL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-AKR1B10 Polyclonal Antibody is a Rabbit antibody targeting AKR1B10. Anti-AKR1B10 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Rabbit) |
| Verified Activity | Sample: A549 Cell Lysate at 40 μg SW480 Cell Lysate at 40 μg Primary: Anti-AKR1B10 (TMAB-02406) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 35 kD Observed band size: 35 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway. |
| Tissue Specificity | Found in many tissues. Highly expressed in small intestine, colon and adrenal gland. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | AKR1B10 is also known as aldose reductase-like-1 (ARL-1), small intestine reductase (SI reductase) or aldose reductase-related protein (ARP or hARP). AKR1B10 is found in many tissues but is predominantly expressed in small intestine, colon and adrenal gland. AKR1B10 is an efficient reductase for aliphatic and aromatic aldehydes. It plays a role in steroid metabolism as well as detoxification of aldehydes in digested food, and may be involved in the retinal-retinoic acid signaling pathway. AKR1B10 is prominently overexpressed in non-small cell lung carcinoma and adenocarcinoma. Cigarette smoking is an independent variable responsible for this overexpression. AKR1B10 may play a role regulating cell proliferation and cellular response to carbonyl stress. |
| Immunogen | KLH conjugated synthetic peptide: human AKR1B10 |
| Antigen Species | Human |
| Gene Name | AKR1B10 |
| Gene ID | |
| Protein Name | Aldo-keto reductase family 1 member B10 |
| Uniprot ID | |
| Function | Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. |
| Molecular Weight | Theoretical: 35 kDa. Actual: 35 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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