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Anti-C6orf25 Polyclonal Antibody

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Catalog No. TMAB-03476

Anti-C6orf25 Polyclonal Antibody is a Rabbit antibody targeting C6orf25. Anti-C6orf25 Polyclonal Antibody can be used in WB.

Anti-C6orf25 Polyclonal Antibody

Anti-C6orf25 Polyclonal Antibody

😃Good
Catalog No. TMAB-03476
Anti-C6orf25 Polyclonal Antibody is a Rabbit antibody targeting C6orf25. Anti-C6orf25 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-C6orf25 Polyclonal Antibody is a Rabbit antibody targeting C6orf25. Anti-C6orf25 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Cow,Sheep)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationIsoform E: Endoplasmic reticulum. Golgi apparatus.Isoform D: Endoplasmic reticulum. Golgi apparatus.Isoform B: Cell membrane; Single-pass type I membrane protein.Isoform A: Cell membrane; Single-pass type I membrane protein.
Tissue SpecificityExpressed in a restricted set of hematopoietic cell lines including the erythroleukemia cell line K-562 and the T-cell leukemia cell lines MOLT-4 and Jurkat. Not detected in the monocyte-like cell line U-937, the B-cell-like cell line Raji, the fibroblast cell lines TK and HeLa, or the natural killer cell lines NKL, NK 62 and YT. Expressed in platelets.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundC6orf25 is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. It is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human C6orf25
Antigen Species
Human
Gene Name
MPIG6B
Gene ID
Protein Name
Megakaryocyte and platelet inhibitory receptor G6b
Uniprot ID
Function
Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart.
Chemical Properties
Molecular WeightTheoretical: 24 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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