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Anti-ADAMTS13 Polyclonal Antibody 2
Catalog No. TMAB-02300 Copy Product Info
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Anti-ADAMTS13 Polyclonal Antibody 2 is a Rabbit antibody targeting . Anti-ADAMTS13 Polyclonal Antibody 2 can be used in IHC-P,IHC-F,IF.
Anti-ADAMTS13 Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-02300
Anti-ADAMTS13 Polyclonal Antibody 2 is a Rabbit antibody targeting . Anti-ADAMTS13 Polyclonal Antibody 2 can be used in IHC-P,IHC-F,IF.
Anti-ADAMTS13 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-ADAMTS13 Polyclonal Antibody 2 is a Rabbit antibody targeting . Anti-ADAMTS13 Polyclonal Antibody 2 can be used in IHC-P,IHC-F,IF. |
| Ig Type | IgG |
| Reactivity | Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse) |
| Verified Activity | 1. Sample: Liver (Mouse) Lysate at 40 μg Primary: Anti-ADAMTS13 (TMAB-02300) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 145 kD Observed band size: 155 kD 2. Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-ADAMTS13 Polyclonal Antibody, Unconjugated (TMAB-02300) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Note=Secretion enhanced by O-fucosylation of TSP type-1 repeats. |
| Tissue Specificity | Plasma. Expressed primarily in liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human ADAMTS13 |
| Antigen Species | Human |
| Gene Name | ADAMTS13 |
| Gene ID | |
| Protein Name | A disintegrin and metalloproteinase with thrombospondin motifs 13 |
| Uniprot ID | |
| Function | Cleaves the vWF multimers in plasma into smaller forms. |
| Molecular Weight | Theoretical: 145 kDa. Actual: 155 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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