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Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody
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Catalog No. TMAB-14459
Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody is a Rabbit antibody targeting Zona pellucida glycoprotein 4. Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody can be used in WB.
Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody
Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody
😃Good
Catalog No. TMAB-14459
Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody is a Rabbit antibody targeting Zona pellucida glycoprotein 4. Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody is a Rabbit antibody targeting Zona pellucida glycoprotein 4. Anti-Zona pellucida glycoprotein 4 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted > extracellular space > extracellular matrix and Cell membrane. |
| Tissue Specificity | Oocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human ZP4 |
| Antigen Species | Human |
| Gene Name | ZP4 |
| Gene ID | |
| Protein Name | Zona pellucida sperm-binding protein 4 |
| Uniprot ID | |
| Function | The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor. |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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