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Anti-Activin A Receptor Type IC Polyclonal Antibody

Catalog No. TMAB-02262 Copy Product Info
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Anti-Activin A Receptor Type IC Polyclonal Antibody is a Rabbit antibody targeting Activin A Receptor Type IC. Anti-Activin A Receptor Type IC Polyclonal Antibody can be used in WB,FCM.

Anti-Activin A Receptor Type IC Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-02262

Anti-Activin A Receptor Type IC Polyclonal Antibody is a Rabbit antibody targeting Activin A Receptor Type IC. Anti-Activin A Receptor Type IC Polyclonal Antibody can be used in WB,FCM.

Anti-Activin A Receptor Type IC Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Activin A Receptor Type IC Polyclonal Antibody is a Rabbit antibody targeting Activin A Receptor Type IC. Anti-Activin A Receptor Type IC Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Rabbit)
Verified Activity
1. Blank control: H9C2 (blue)
Isotype Control Antibody: Rabbit IgG (orange);
Secondary Antibody: Goat anti-rabbit IgG-FITC (white blue),
Dilution: 1:100 in 1 X PBS containing 0.5% BSA;
Primary Antibody Dilution: 3 μl in 100 μL1X PBS containing 0.5% BSA (green).
2. Sample:
Heart (Mouse) Lysate at 40 μg
Primary: Anti-Activin A Receptor Type IC (TMAB-02262) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD
3. Sample:
HepG2 (Human) Cell Lysate at 30 μg
Hela (Human) Cell Lysate at 30 μg
Primary: Anti-Activin A Receptor Type IC (TMAB-02262) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD
4. Sample:
Placenta (Mouse) Lysate at 40 μg
Primary: Anti-Activin A Receptor Type IC (TMAB-02262) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD
Application
Recommended Dose
WB: 1:500-2000; FCM: 3μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityPresent in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSerine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ACTRIC/Activin A Receptor Type IC
Antigen Species
Human
Gene Name
ACVR1C
Gene ID
Protein Name
Activin receptor type-1C
Uniprot ID
Function
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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