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Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody
Catalog No. TMAB-11091 Copy Product Info
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Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p57 Kip2 (Thr310). Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-11091
Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p57 Kip2 (Thr310). Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-p57 Kip2
(Thr310) Polyclonal Antibody
(Thr310) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p57 Kip2 (Thr310). Anti-Phospho-p57 Kip2 (Thr310) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (mouse pancreas); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Phospho-p57 Kip2 (Thr310)) Polyclonal Antibody, Unconjugated (TMAB-11091) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human p57 Kip2 around the phosphorylation site of Thr310 |
| Antigen Species | Human |
| Gene Name | CDKN1C |
| Gene ID | |
| Protein Name | Cyclin-dependent kinase inhibitor 1C |
| Uniprot ID | |
| Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
| Molecular Weight | Theoretical: 35 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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