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Anti-LMOD2 Polyclonal Antibody

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Catalog No. TMAB-08344

Anti-LMOD2 Polyclonal Antibody is a Rabbit antibody targeting LMOD2. Anti-LMOD2 Polyclonal Antibody can be used in WB.

Anti-LMOD2 Polyclonal Antibody

Anti-LMOD2 Polyclonal Antibody

😃Good
Catalog No. TMAB-08344
Anti-LMOD2 Polyclonal Antibody is a Rabbit antibody targeting LMOD2. Anti-LMOD2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-LMOD2 Polyclonal Antibody is a Rabbit antibody targeting LMOD2. Anti-LMOD2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Pig,Cow,Horse,Sheep)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificitySpecifically expressed in heart and skeletal muscles. Not expressed in other tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMembers of the Leiomodin protein family are closely related to the tropomodulin family of actin filament pointed end-capping proteins. Leiomodins are actin-binding proteins that act as strong filament nucleators in muscle cells. Leiomodin 1 is highly expressed in a variety of tissues that contain smooth muscle, therefore it is also known as smooth muscle Leiomodin, or SM-Lmod. Also designated C-Lmod, Leiomodin 3 is found in several types of fetal tissue and is involved in tropomyosin binding. Leiomodin 2, also known as C-LMOD or LMOD2, is a 547 amino acid protein that is specifically expressed in heart and skeletal muscles. Leiomodin 2 binds to tropomyosin and may block the elongation and depolymerization of actin filaments at their pointed end. Leiomodin 2 is encoded by a gene that is located near the hypertrophic cardiomyopathy locus CMH6 on chromosome 7, suggesting that Leiomodin 2 may be involved in that disease process. Leiomodin 2 is expressed as three alternatively spliced variants.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human LMOD2
Antigen Species
Human
Gene Name
LMOD2
Gene ID
442721
Protein Name
Leiomodin-2
Uniprot ID
Q6P5Q4
Function
May block the elongation and depolymerization of the actin filaments at the pointed end.
Chemical Properties
Molecular WeightTheoretical: 62 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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