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Anti-CCR3 Polyclonal Antibody 2
Catalog No. TMAB-03801 Copy Product Info
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Anti-CCR3 Polyclonal Antibody 2 is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody 2 can be used in WB.
Anti-CCR3 Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-03801
Anti-CCR3 Polyclonal Antibody 2 is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody 2 can be used in WB.
Anti-CCR3 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CCR3 Polyclonal Antibody 2 is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Rat) |
| Verified Activity | 1Sample: Lane 1: Mouse Lymph node tissue lysates Lane 2: Mouse Lung tissue lysates Primary: Anti-CCR3 (TMAB-03801) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 59 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described. |
| Immunogen | KLH conjugated synthetic peptide: mouse CCR3 |
| Antigen Species | Mouse |
| Gene Name | CCR3 |
| Gene ID | |
| Protein Name | C-C chemokine receptor type 3 |
| Uniprot ID | |
| Function | Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. |
| Molecular Weight | Theoretical: 41 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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