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Anti-CCR3 Polyclonal Antibody 2

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Catalog No. TMAB-03801

Anti-CCR3 Polyclonal Antibody 2 is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody 2 can be used in WB.

Anti-CCR3 Polyclonal Antibody 2

Anti-CCR3 Polyclonal Antibody 2

😃Good
Catalog No. TMAB-03801
Anti-CCR3 Polyclonal Antibody 2 is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody 2 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CCR3 Polyclonal Antibody 2 is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Rat)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityIn eosinophils as well as trace amounts in neutrophils and monocytes.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse CCR3
Antigen Species
Mouse
Gene Name
CCR3
Gene ID
12771
Protein Name
C-C chemokine receptor type 3
Uniprot ID
P51678
Function
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
Chemical Properties
Molecular WeightTheoretical: 41 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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