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Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody
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Catalog No. TMAB-11066
Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NR1D1 (Ser55+Ser59). Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody
Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody
😃Good
Catalog No. TMAB-11066
Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NR1D1 (Ser55+Ser59). Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NR1D1 (Ser55+Ser59). Anti-Phospho-NR1D1 (Ser55+Ser59) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Cow,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus (Potential). |
| Tissue Specificity | Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | NR1D1, a NR1 Thyroid Hormone-Like Receptor, is encoded by the same genomic locus as, but transcribed from the opposite strand of, Thyroid Hormone Receptor Alpha (TR Alpha). NR1D1 is a target of Nuclear Receptor ROR Alpha and a transcription regulator that has been shown to affect myocyte differentiation, adipogenesis, and lipoprotein metabolism. Mice lacking NR1D1 show abnormal postnatal cerebellar development. NR1D1 expression has been documented in human skeletal muscle and a variety of mouse and rat tissues. ESTs have been isolated from human tissue libraries, including cancerous adrenal, blood, brain, breast, colon, duodenum, fetus, head/neck, kidney, lung, skeletal muscle, skin, synovium, uterus, normal brain, breast, colon, eye, heart, pancreas, pituitary, prostate, skeletal muscle, skin, testis and thyroid. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human REV-ERB alpha around the phosphorylation site of Ser55/59 |
| Antigen Species | Human |
| Gene Name | NR1D1 |
| Gene ID | |
| Protein Name | Nuclear receptor subfamily 1 group D member 1 |
| Function | Functions as a constitutive transcriptional repressor. In collaboration with SP1, activates GJA1 transcription. Possible receptor for triiodothyronine. |
| Molecular Weight | Theoretical: 67 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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