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Anti-hydrogen exchanger 3 Polyclonal Antibody 3
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Catalog No. TMAB-07465
Anti-hydrogen exchanger 3 Polyclonal Antibody 3 is a Rabbit antibody targeting hydrogen exchanger 3. Anti-hydrogen exchanger 3 Polyclonal Antibody 3 can be used in WB.
Anti-hydrogen exchanger 3 Polyclonal Antibody 3
Anti-hydrogen exchanger 3 Polyclonal Antibody 3
😃Good
Catalog No. TMAB-07465
Anti-hydrogen exchanger 3 Polyclonal Antibody 3 is a Rabbit antibody targeting hydrogen exchanger 3. Anti-hydrogen exchanger 3 Polyclonal Antibody 3 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-hydrogen exchanger 3 Polyclonal Antibody 3 is a Rabbit antibody targeting hydrogen exchanger 3. Anti-hydrogen exchanger 3 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Pig,Cow,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. In intestinal epithelial cells, localizes to the ileal brush border. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells. |
| Immunogen | KLH conjugated synthetic peptide: human hydrogen exchanger 3 |
| Antigen Species | Human |
| Gene Name | SLC9A3 |
| Gene ID | |
| Protein Name | Sodium/hydrogen exchanger 3 |
| Uniprot ID | |
| Function | Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. |
| Molecular Weight | Theoretical: 93 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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