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Anti-Cyclophilin B Polyclonal Antibody
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Catalog No. TMAB-04854
Anti-Cyclophilin B Polyclonal Antibody is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Cyclophilin B Polyclonal Antibody
Anti-Cyclophilin B Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-04854
Anti-Cyclophilin B Polyclonal Antibody is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
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| Description | Anti-Cyclophilin B Polyclonal Antibody is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Cyclophilin B) Polyclonal Antibody, Unconjugated (TMAB-04854) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression. |
| Immunogen | KLH conjugated synthetic peptide: human Cyclophilin B |
| Antigen Species | Human |
| Gene Name | PPIB |
| Gene ID | |
| Protein Name | Peptidyl-prolyl cis-trans isomerase B |
| Uniprot ID | |
| Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| Molecular Weight | Theoretical: 20 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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