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Anti-Cyclophilin B Polyclonal Antibody

Catalog No. TMAB-04854 Copy Product Info
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Anti-Cyclophilin B Polyclonal Antibody is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Cyclophilin B Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04854

Anti-Cyclophilin B Polyclonal Antibody is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Cyclophilin B Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Cyclophilin B Polyclonal Antibody is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Cyclophilin B) Polyclonal Antibody, Unconjugated (TMAB-04854) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Cyclophilin B
Antigen Species
Human
Gene Name
PPIB
Gene ID
Protein Name
Peptidyl-prolyl cis-trans isomerase B
Uniprot ID
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Chemical Properties
Molecular WeightTheoretical: 20 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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