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Anti-PDE4B Polyclonal Antibody

😃Good
Catalog No. TMAB-10110

Anti-PDE4B Polyclonal Antibody is a Rabbit antibody targeting PDE4B. Anti-PDE4B Polyclonal Antibody can be used in WB.

Anti-PDE4B Polyclonal Antibody

Anti-PDE4B Polyclonal Antibody

😃Good
Catalog No. TMAB-10110
Anti-PDE4B Polyclonal Antibody is a Rabbit antibody targeting PDE4B. Anti-PDE4B Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PDE4B Polyclonal Antibody is a Rabbit antibody targeting PDE4B. Anti-PDE4B Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityExpressed in brain, heart, lung and skeletal muscle.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PDE4B
Antigen Species
Human
Gene Name
PDE4B
Gene ID
Protein Name
cAMP-specific 3', 5'-cyclic phosphodiesterase 4B
Uniprot ID
Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Chemical Properties
Molecular WeightTheoretical: 107 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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