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Anti-HSP105 Polyclonal Antibody
😃Good
Catalog No. TMAB-07331
Anti-HSP105 Polyclonal Antibody is a Rabbit antibody targeting HSP105. Anti-HSP105 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-HSP105 Polyclonal Antibody
Anti-HSP105 Polyclonal Antibody
😃Good
Catalog No. TMAB-07331
Anti-HSP105 Polyclonal Antibody is a Rabbit antibody targeting HSP105. Anti-HSP105 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HSP105 Polyclonal Antibody is a Rabbit antibody targeting HSP105. Anti-HSP105 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Heat Shock Proteins are ubiquitously expressed in all organisms. They are induced when a cell undergoes various types of environmental stresses like heat, cold and oxygen deprivation. They are characterized by their role as molecular chaperones. Heat shock protein (HSP) 105 exists as two isoforms; alpha and beta which belong to the HSP105/HSP110 protein family. HSP105 acts as both a chaperone to prevent thermal aggregation of proteins and as a regulator of mammalian cells. The HSP105 isoforms are found in the cytoplasm but not in the nucleoli under non-stressed and stressed conditions. |
| Immunogen | KLH conjugated synthetic peptide: human HSP105 |
| Antigen Species | Human |
| Gene Name | HSPH1 |
| Gene ID | |
| Protein Name | Heat shock protein 105 kDa |
| Uniprot ID | |
| Function | Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity). |
| Molecular Weight | Theoretical: 97 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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