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Anti-TCF7L1 Polyclonal Antibody
Catalog No. TMAB-13426 Copy Product Info
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Anti-TCF7L1 Polyclonal Antibody is a Rabbit antibody targeting TCF7L1. Anti-TCF7L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-TCF7L1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13426
Anti-TCF7L1 Polyclonal Antibody is a Rabbit antibody targeting TCF7L1. Anti-TCF7L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-TCF7L1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TCF7L1 Polyclonal Antibody is a Rabbit antibody targeting TCF7L1. Anti-TCF7L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Cow) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Human skin); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TCF7L1) Polyclonal Antibody, Unconjugated (TMAB-13426) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010] |
| Immunogen | KLH conjugated synthetic peptide: human TCF7L1 |
| Antigen Species | Human |
| Gene Name | TCF7L1 |
| Gene ID | |
| Protein Name | Transcription factor 7-like 1 |
| Uniprot ID | |
| Function | Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance. |
| Molecular Weight | Theoretical: 63 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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