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Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody
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Catalog No. TMAB-11001
Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MNK1 (Thr250). Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody
Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-11001
Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MNK1 (Thr250). Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MNK1 (Thr250). Anti-Phospho-MNK1 (Thr250) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (mouse placenta tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MNK1 (Thr250)) Polyclonal Antibody, Unconjugated (TMAB-11001) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm and Cytoplasm. Nucleus. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012] |
| Immunogen | KLH conjugated synthesised phosphopeptide: human MNK1 around the phosphorylation site of Thr250 |
| Antigen Species | Human |
| Gene Name | MKNK1 |
| Gene ID | |
| Protein Name | MAP kinase-interacting serine/threonine-protein kinase 1 |
| Uniprot ID | |
| Function | May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. |
| Molecular Weight | Theoretical: 51 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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