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Anti-ASPSCR1 Polyclonal Antibody

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Catalog No. TMAB-02879

Anti-ASPSCR1 Polyclonal Antibody is a Rabbit antibody targeting ASPSCR1. Anti-ASPSCR1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-ASPSCR1 Polyclonal Antibody

Anti-ASPSCR1 Polyclonal Antibody

😃Good
Catalog No. TMAB-02879
Anti-ASPSCR1 Polyclonal Antibody is a Rabbit antibody targeting ASPSCR1. Anti-ASPSCR1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ASPSCR1 Polyclonal Antibody is a Rabbit antibody targeting ASPSCR1. Anti-ASPSCR1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndomembrane system; Peripheral membrane protein.
Tissue SpecificityUbiquitous. Highly expressed in testis, heart, skeletal muscle and pancreas.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGlut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TUG/ASPC
Antigen Species
Human
Gene Name
ASPSCR1
Gene ID
79058
Protein Name
Tether containing UBX domain for GLUT4
Uniprot ID
Q9BZE9
Function
Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin. Modulates the amount of GLUT4 that is available at the cell surface.
Chemical Properties
Molecular WeightTheoretical: 60 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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