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Anti-LMX1A Polyclonal Antibody
😃Good
Catalog No. TMAB-08348
Anti-LMX1A Polyclonal Antibody is a Rabbit antibody targeting LMX1A. Anti-LMX1A Polyclonal Antibody can be used in WB.
Anti-LMX1A Polyclonal Antibody
Anti-LMX1A Polyclonal Antibody
😃Good
Catalog No. TMAB-08348
Anti-LMX1A Polyclonal Antibody is a Rabbit antibody targeting LMX1A. Anti-LMX1A Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-LMX1A Polyclonal Antibody is a Rabbit antibody targeting LMX1A. Anti-LMX1A Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Isoform 1 is expressed in many tissues. Not found in heart, liver, spleen and testis. Relatively highly expressed in fetal brain. Isoform LMX1A-4B is expressed in testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | LMX1A belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. Two isoforms of LMX1A exist due to alternative splicing. Isoform 1 represents the full length protein and is expressed in many tissues including fetal brain, but is absent in heart, liver, spleen and testis. The second isoform, designated LMX1A-4AB, lacks amino acids 1-249 and is expressed in testis. |
| Immunogen | KLH conjugated synthetic peptide: human LMX1A |
| Antigen Species | Human |
| Gene Name | LMX1A |
| Gene ID | |
| Protein Name | LIM homeobox transcription factor 1-alpha |
| Uniprot ID | |
| Function | Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae. |
| Molecular Weight | Theoretical: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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