Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2
😃Good
Catalog No. TMAB-10344
Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ATF2 (Ser480). Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 can be used in WB.
Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2
Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2
😃Good
Catalog No. TMAB-10344
Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ATF2 (Ser480). Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ATF2 (Ser480). Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Abundant expression seen in the brain. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human ATF2 around the phosphorylation site of Ser480 |
| Antigen Species | Human |
| Gene Name | ATF2 |
| Gene ID | |
| Protein Name | Cyclic AMP-dependent transcription factor ATF-2 |
| Uniprot ID | |
| Function | Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex. |
| Molecular Weight | Theoretical: 45 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 | purchase Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 | Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 cost | order Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 | Anti-Phospho-ATF2 (Ser480) Polyclonal Antibody 2 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.