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Anti-Phospho-14-3-3 beta+zeta (Ser186/Ser184) Polyclonal Antibody

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Catalog No. TMAB-10277 Copy Product Info
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Anti-Phospho-14-3-3 beta+zeta (Ser186/Ser184) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 beta+zeta (Ser186/Ser184). Anti-Phospho-14-3-3 beta+zeta (Ser186/Ser184) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Anti-Phospho-14-3-3 beta+zeta
(Ser186/Ser184) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-14-3-3 beta+zeta (Ser186/Ser184) Polyclonal Antibody is a Rabbit antibody targeting Phospho-14-3-3 beta+zeta (Ser186/Ser184). Anti-Phospho-14-3-3 beta+zeta (Ser186/Ser184) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 0.2μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research Background14-3-3 are activates tyrosine and tryptophan hydroxylases in the presence of Ca (2+)/calmodulin-dependent protein kinase II, and strongly activates protein kinase C. Is probably a multifunctional regulator of the cell signaling processes mediated by both kinases. Activates the ADP-ribosyltransferase (exoS) activity of bacterial origin. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It belongs to the 14-3-3 family. This antibody is reactive with 14-3-3 Alpha, Beta, Gamma, Delta, Epsilon.
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human 14-3-3 beta + zeta around the phosphorylation site of Ser186 / Ser184
Antigen Species
Human
Gene Name
YWHAB
Gene ID
Protein Name
14-3-3 protein beta/alpha
Uniprot ID
Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Chemical Properties
Molecular WeightTheoretical: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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